TOP WHERE TO PHENOBARBITAL SECRETS

Monitor Closely (one)phenobarbital will minimize the extent or result of fentanyl transmucosal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Coadministration of fentanyl with CYP3A4 inducers could lead into a decrease in fentanyl plasma concentrations, insufficient efficacy or, perhaps, development of the